Canine keratomycosis in 11 dogs: a case series (2000-2011)

Keratomycosis is rarely reported in dogs. The purpose of this study was to review the signalment, clinical characteristics, predisposing factors, and outcome of 11 cases of canine keratomycosis. Medical records of included dogs were reviewed and follow-up information was obtained by re-examination of patients following their initial diagnosis. All 11 patients possessed predisposing factors for fungal keratitis, including an underlying endocrinopathy, pre-existing corneal disease, intraocular surgery, and/or prolonged use of either topical antibiotics or corticosteroids at the time of initial examination. Diagnostic techniques included corneal cytology demonstrating yeast or hyphae in 6 of 11 eyes, and fungal cultures with positive results in 7 of 11 eyes. Fungal organisms isolated included Cladosporium spp. (n = 1), Chrysosporium spp. (n = 1), Curvularia spp. (n = 2), Aspergillus spp. (n = 1), Penicillium spp. (n = 1), and Phialemonium spp. (n = 1). Of the 11 patients, 6 responded to medical management alone. Two resolved after a superficial keratectomy, and three were enucleated due to either endophthalmitis or progression of corneal disease. This study identified potential risk factors for developing fungal keratitis.