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Related Experiment Videos

Prostatic involvement in Wegener's granulomatosis.

T J Stillwell1, R A DeRemee, T J McDonald

  • 1Department of Urology, Mayo Clinic, Rochester, Minnesota 55905.

The Journal of Urology
|November 1, 1987
PubMed
Summary

Prostate involvement in Wegener's granulomatosis is rare but can cause urinary issues. Early medical treatment may help, but severe cases might require prostatectomy.

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Ahead to the past.

Mayo Clinic proceedings·1999

Area of Science:

  • Urology
  • Rheumatology
  • Pathology

Background:

  • Wegener's granulomatosis is a rare autoimmune disease.
  • Prostate gland involvement is an uncommon manifestation.
  • Necrotizing granulomas and vasculitis are characteristic histopathological findings.

Observation:

  • Three cases of Wegener's granulomatosis affecting the prostate are presented.
  • Patients experienced symptoms such as gross hematuria and obstructive voiding.
  • Urinary retention was a noted complication.

Findings:

  • Histological examination confirmed necrotizing granulomas and vasculitis in the prostate.
  • The condition can lead to significant lower urinary tract symptoms.
  • Surgical intervention (prostatectomy) may be necessary for severe symptoms.

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Implications:

  • Understanding the natural history of Wegener's granulomatosis is crucial for management.
  • Aggressive medical therapy can be a successful initial treatment approach.
  • This highlights the importance of considering systemic diseases in urological presentations.