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Immunological function and nutritional assessment.

L Dominioni1, R Dionigi

  • 1Department of Surgery, Sezione di Patologia Chirurgica, University of Pavia, Italy.

JPEN. Journal of Parenteral and Enteral Nutrition
|September 1, 1987
PubMed
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Simple immunologic tests, like total lymphocyte count, are valuable for assessing nutritional status. Other complex tests are better suited for research due to practical limitations and confounding clinical factors.

Area of Science:

  • Clinical Nutrition
  • Immunology

Background:

  • Numerous immunologic function tests exist for nutritional assessment.
  • Many complex tests require specialized skills, are time-consuming, and offer limited clinical value compared to simpler methods.

Purpose of the Study:

  • To identify practical and reliable immunologic indicators for routine nutritional assessment.
  • To differentiate between clinically applicable tests and those suitable for research.

Main Methods:

  • Review of various immunologic tests for their simplicity, reproducibility, and reliability in assessing nutritional status.
  • Consideration of confounding clinical variables affecting immunologic test results.

Main Results:

  • Total lymphocyte count and skin tests are identified as practical, reliable indicators for routine nutritional assessment.

Related Experiment Videos

  • Most other immunologic measurements are currently best utilized as research tools.
  • Acute-phase protein response measurement offers a functional assessment of nutritional status, as malnutrition suppresses it.

    • Conclusions:

    • Routine nutritional assessment can effectively utilize simple immunologic tests like total lymphocyte count and skin tests.
    • Clinical variables unrelated to nutrition can significantly impact immunologic test results, necessitating careful interpretation.
    • Measuring the acute-phase protein response provides a functional indicator of nutritional status.