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Updated: May 3, 2026

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation
Published on: August 1, 2010
Primitive intrapericardial teratoma associated with yolk sac tumour
Enrico Cetrano1, Angelo Polito2, Adriano Carotti1
11Unit of Cardiac Surgery,Bambino Gesù Children's Hospital,IRCCS,Rome,Italy.
Abstract:
An intrapericardial vacuolated mass compressing and displacing the heart was diagnosed by echocardiography in a foetus of 22 weeks gestation. The birth was induced for early signs of foetal distress at 29 weeks and, after two initial pericardial evacuation procedures, the tumour was resected radically 7 days after birth at a weight of 1.55 kg. Mass histology showed teratoma associated with yolk sac tumour. We comment on the overall approach adopted after foetal diagnosis and the histopathological features of the tumour, and try to draw conclusions on patient outcome data.
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