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Updated: May 3, 2026

Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning
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PIKE is essential for oligodendroglia development and CNS myelination

Chi Bun Chan1, Xia Liu, Lixia Zhao

  • 1Department of Pathology and Laboratory Medicine, Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322.

Proceedings of the National Academy of Sciences of the United States of America
|January 23, 2014
PubMed
Summary

Phosphoinositide-3 kinase enhancer L (PIKE-L) is crucial for oligodendrocyte development and myelin formation. Its depletion impairs oligodendrocyte differentiation and myelination, highlighting PIKE

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