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Related Experiment Videos

Cow's milk allergenicity.

Sophia Tsabouri, Kostas Douros, Kostas N Priftis1

  • 1Child Health Department, University of Ioannina Medical School, Ioannina, Greece. stsabouri@gmail.com.

Endocrine, Metabolic & Immune Disorders Drug Targets
|January 24, 2014
PubMed
Summary

Milk allergy is a common childhood food allergy. Hydrolyzed cow's milk formulas can be safe for infants with milk allergy, reducing allergenicity.

Area of Science:

  • Pediatric Allergy and Immunology
  • Food Science and Technology

Background:

  • Milk allergy is the most prevalent food allergy in childhood.
  • Early introduction of cow's milk formula contributes to its high prevalence in infants.
  • Key allergens include caseins, alpha-lactalbumin, and beta-lactoglobulin.

Purpose of the Study:

  • To review clinical and epidemiological aspects of milk allergy.
  • To present data on the structure and function of major cow's milk allergens.
  • To discuss strategies for reducing milk allergenicity and managing milk allergy.

Main Methods:

  • Literature review of clinical and epidemiological data.
  • Analysis of scientific data on cow's milk allergen structure and function.
  • Evaluation of processing methods for reducing milk allergenicity.

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Main Results:

  • Identified major cow's milk allergens and discussed their roles.
  • Highlighted the efficacy of processing methods, particularly hydrolysis, in reducing allergenicity.
  • Reported cross-reactivity between different mammalian milks and other animal proteins.

Conclusions:

  • Cow's milk allergy is a significant concern in pediatric populations.
  • Hydrolyzed formulas offer a safer alternative for infants with milk allergy.
  • Understanding allergen structure and cross-reactivity is crucial for management.