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Related Experiment Videos

Polymorphonuclear leukocyte chemotaxis in generalized pustular psoriasis.

B D Zelickson1, M R Pittelkow, S A Muller

  • 1Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905.

Acta Dermato-Venereologica
|January 1, 1987
PubMed
Summary

Patients with generalized pustular psoriasis may exhibit a specific defect in polymorphonuclear leukocyte (PMNL) chemotaxis towards serum-derived attractants, even during quiescent disease phases.

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Area of Science:

  • Immunology
  • Dermatology
  • Cell Biology

Background:

  • Generalized pustular psoriasis is a severe inflammatory skin condition.
  • Polymorphonuclear leukocytes (PMNLs) play a crucial role in immune responses.
  • Chemotaxis, the directed movement of cells, is vital for PMNL function.