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Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
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Probable primary cutaneous histoplasmosis in a patient infected with HIV

E Gomez-Moyano1, V Crespo-Erchiga, A Vera-Casaño

  • 1Dermatology, Carlos Haya Hospital, Malaga, Spain.

Journal De Mycologie Medicale
|January 24, 2014
PubMed

Insights

This case study details a probable cutaneous histoplasmosis infection in an immunocompromised man following trauma. Diagnosis confirmed localized fungal infection without systemic spread.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Histoplasmosis is a fungal infection caused by Histoplasma capsulatum.
  • Infections typically arise from inhaling fungal spores.
  • Clinical presentation varies with host immunity and inoculation site.

Purpose of the Study:

  • To report a case of probable cutaneous histoplasmosis.
  • To highlight a rare presentation post-trauma in an immunocompromised individual.

Main Methods:

  • Histological examination of affected tissue.
  • Mycological analysis for fungal identification.

Main Results:

  • A 26-year-old male from Paraguay presented with skin lesions after trauma.
  • The patient was co-infected with human immunodeficiency virus.
  • Histological and mycological findings confirmed cutaneous histoplasmosis.
  • No evidence of disseminated or systemic fungal infection was detected.

Conclusions:

  • Cutaneous histoplasmosis can manifest following trauma, particularly in immunocompromised patients.
  • Prompt diagnosis via histological and mycological methods is crucial.
  • Localized cutaneous form suggests a favorable prognosis without systemic involvement.

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