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Updated: May 3, 2026

Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct
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Melioidosis of salivary glands with coexisting diabetes: management of a difficult case

M Panduranga Kamath1, Kiran Bhojwani, Mahabala Chakrapani

  • 1Department of Otolaryngology, Kasturba Medical College, 1st Floor, Yenepoya Shoppers Gallery, Opp. Bishop's House, Near Karnataka Bank, Kodialbail, Mangalore 575003 Karnataka, India. kamathmp@yahoo.co.in.

Ear, Nose, & Throat Journal
|January 24, 2014
PubMed

Insights

Melioidosis, a serious infection caused by Burkholderia pseudomallei, rarely affects salivary glands. This case highlights successful conservative management in a diabetic patient, emphasizing early diagnosis and treatment for this endemic disease.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Endocrinology

Background:

  • Melioidosis is an infectious disease caused by Burkholderia pseudomallei, endemic in Southeast Asia and Northern Australia.
  • Diabetes mellitus is a significant risk factor, increasing susceptibility to melioidosis by up to 100-fold.

Observation:

  • A rare case of melioidosis affecting the parotid and submandibular glands is presented.
  • The patient had coexisting diabetes mellitus, a known risk factor for severe infections.

Findings:

  • The rare presentation of salivary gland melioidosis was successfully treated with a conservative approach.
  • Intravenous ceftazidime followed by oral trimethoprim/sulfamethoxazole and doxycycline formed the treatment regimen.

Implications:

  • This case underscores the importance of considering melioidosis in endemic areas, especially in diabetic patients with unusual presentations.
  • Conservative management with appropriate antibiotics can be effective for localized salivary gland melioidosis.
  • Highlights the need for increased awareness of Burkholderia pseudomallei infections in clinical practice.

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