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Updated: May 3, 2026

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Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
Published on: January 19, 2014
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Evidence of in utero transmission of classical scrapie in sheep
John Spiropoulos1, Stephen A C Hawkins, Marion M Simmons
1Animal Health and Veterinary Laboratories Agency (AHVLA) Weybridge, Addlestone, Surrey, United Kingdom.
Journal of Virology
|January 24, 2014
Abstract:
Classical scrapie is one of the transmissible spongiform encephalopathies (TSEs), a group of fatal infectious diseases that affect the central nervous system (CNS). Classical scrapie can transmit laterally from ewe to lamb perinatally or between adult animals. Here we report detection of infectivity in tissues of an unborn fetus, providing evidence that in utero transmission of classical scrapie is also possible.

