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Updated: May 3, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
N-(1,3-Benzo-thia-zol-2-yl)acetamide
Prakash S Nayak1, B Narayana1, Jerry P Jasinski2
1Department of Studies in Chemistry, Mangalore University, Mangalagangotri 574 199, India.
This study details the crystal structure of a C9H8N2OS compound, revealing specific dihedral angles and hydrogen bonding patterns. The molecules form dimers which then stack in a defined crystalline arrangement.
Area of Science:
- Crystallography
- Chemical Physics
Background:
- Understanding molecular interactions and crystal packing is crucial in materials science.
- The compound C9H8N2OS presents an interesting structure for crystallographic analysis.
Purpose of the Study:
- To elucidate the crystal structure of the title compound C9H8N2OS.
- To analyze the molecular conformation and intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the crystal structure.
- Analysis of dihedral angles and hydrogen bonding networks was performed.
Main Results:
- The asymmetric unit contains two molecules (A and B) of C9H8N2OS.
- Dihedral angles between the 1,3-benzothiazol-2-yl ring and acetamide group are 2.7(4)° (A) and 7.2(2)° (B).
- N-H⋯N hydrogen bonds form dimers (R2(2)(8) loops), which stack along the [100] direction.
Conclusions:
- The crystal structure of C9H8N2OS is characterized by specific molecular conformations and a defined hydrogen-bonding network.
- The observed dimer formation and stacking provide insights into the solid-state behavior of this compound.
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