Related Experiment Video
Updated: May 3, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
1-Acetyl-5-(4-fluoro-phen-yl)-2-sulfanyl-ideneimidazolidin-4-one
Soh-Ichi Kitoh1, Yijing Feng1, Shuhei Fujinami1
1Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.
Abstract:
In the title compound, C11H9FN2O2S, the 2-sulfanylideneimidazolidin-4-one moiety is essentially planar, with a maximum deviation of 0.0183 (14) Å. The mean plane of this moiety is approximately coplanar with the attached acetyl group and perpendicular to the benzene ring, making dihedral angles of 9.70 (14) and 86.70 (6)°, respectively. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds between the amide NH and acetyl C=O groups, forming a C(6) chain along the a-axis direction.

