Related Experiment Video
Updated: May 3, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
Published on: March 20, 2017
Bariatric surgery in moderately obese patients: a prospective study
M Cerci1, M I Bellini1, F Russo1
1Bariatric Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Policlinico di Tor Vergata, Viale Oxford, 81-00133 Roma, Italy.
Bariatric surgery effectively treats moderate obesity (BMI 30-35 kg/m²), significantly reducing BMI and improving comorbidities like type 2 diabetes and hypertension. This study supports its use in selected patients.
Area of Science:
- Bariatric Surgery
- Metabolic Disorders
- Obesity Management
Background:
- Moderate obesity (BMI 30-35 kg/m²) affects 25% of Western populations.
- Bariatric surgery's role in this demographic is debated, often reserved for comorbidities.
- Conservative medical treatment is the current standard for moderate obesity.
Purpose of the Study:
- To evaluate the efficacy and outcomes of bariatric surgery in patients with moderate obesity and comorbidities.
- To assess the impact of bariatric surgery on BMI, type 2 diabetes mellitus (T2DM), hypertension, and obstructive sleep apnea (OSA).
Main Methods:
- A cohort of 25 patients with Grade I obesity and comorbidities underwent laparoscopic bariatric surgery (gastric bypass or sleeve gastrectomy).
- Patients were selected based on BMI (30-35 kg/m²) and presence of T2DM, hypertension, or OSA.
- Follow-up was conducted over a mean of 12.4 months.
Main Results:
- Average BMI decreased from 33.2 kg/m² to 27.2 kg/m² (a 6-point reduction).
- Significant improvements were observed in comorbidities: 86% of T2DM patients discontinued medication, 87% of hypertension patients achieved remission or improvement, and OSA patients experienced complete remission.
- One postoperative complication (trocar site bleeding) was successfully managed.
Conclusions:
- Bariatric surgery is a valid and effective treatment option for selected patients with moderate obesity (BMI 30-35 kg/m²) and associated comorbidities.
- The findings suggest potential for broader application of bariatric surgery in this patient group in the future.
- Surgical intervention can lead to substantial improvements in metabolic health and quality of life.
Related Concept Videos
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Drug Dosing: Obese Patients
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:

