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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
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Epididymoorchitis as the first finding in patients with brucellosis
Ayhan Karaköse1, Mehmet Bilgehan Yuksel2, Ozgü Aydoğdu1
1Izmir University School of Medicine, Department of Urology, 35200 Izmir, Turkey.
Advances in Urology
|January 24, 2014
Summary
Brucellosis can present as epididymoorchitis, a rare initial symptom of acute scrotal pain in men. Early diagnosis and treatment with antibiotics and conservative management are effective, with no observed relapses.
Area of Science:
- Infectious Diseases
- Urology
- Microbiology
Background:
- Brucellosis is a zoonotic infection with diverse clinical manifestations.
- Acute scrotal pain is an uncommon initial presentation of brucellosis.
Purpose of the Study:
- To evaluate male patients diagnosed with brucellosis presenting with epididymoorchitis as the primary symptom.
- To assess the clinical, laboratory, and radiological features of brucellar epididymoorchitis.
Main Methods:
- Retrospective review of seven male patients with acute scrotal pain and suspected brucellosis.
- Evaluation of clinical presentation, serological tests (Rose-Bengal, Wright, Coombs), and treatment outcomes.
Main Results:
- All seven patients presented with scrotal pain, swelling, and increased sweating.
- Positive Rose-Bengal and Wright agglutination tests were observed in all patients.
- Antibiotic and conservative treatment resulted in no relapses.
Conclusions:
- Epididymoorchitis due to brucellosis should be considered in the differential diagnosis of acute scrotal pain in endemic areas.
- Clinical and serological findings are sufficient for diagnosis.
- Conservative management with antibiotics is effective for brucellar epididymoorchitis.
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