Related Experiment Video
Updated: May 3, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Random synchronous malignancy in male breast: a case report.
Manjit Sarma1, Chaitanya Borde1, Padma Subramanyam1
1Department of Nuclear Medicine & PET CT, Amrita Institute of Medical Sciences (Amrita Vishwa Vidyapeetham), Cochin, Kerala, India.
This case report highlights a rare instance of synchronous male breast cancer discovered incidentally during staging for base of tongue cancer. Whole body imaging revealed this dual malignancy, emphasizing its utility in detecting unexpected cancers.
Area of Science:
- Oncology
- Radiology
- Nuclear Medicine
Background:
- Synchronous malignancies, particularly in the head and neck and upper aerodigestive tract, are well-documented.
- Male breast cancer is a rare diagnosis, and synchronous presentations are even less common.
Observation:
- A patient with known base of tongue squamous cell carcinoma underwent whole body 18-fluorine deoxyglucose positron emission tomography and computed tomography ((18)F-FDG PET/CT) for staging.
- An incidental finding of a breast lesion was detected during the whole body scan.
- Histopathological analysis confirmed the breast lesion to be invasive ductal carcinoma.
Findings:
- The (18)F-FDG PET/CT successfully identified a synchronous, incidentally detected invasive ductal carcinoma of the male breast.
- This case represents a rare occurrence of dual primary malignancies involving the base of the tongue and male breast.
Implications:
- Whole body (18)F-FDG PET/CT imaging plays a crucial role in detecting unexpected synchronous primary malignancies.
- This case underscores the importance of thorough evaluation of incidental findings, even in rare presentations like male breast cancer.
Related Concept Videos
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Abnormal Proliferation
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

