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Related Concept Videos

Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

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Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
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Peptic Ulcer Disease I: Introduction01:25

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Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
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Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal...
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Peptic Ulcer Disease II: Pathophysiology01:24

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Peptic ulcer disease develops when protective mechanisms of the gastrointestinal mucosa are overwhelmed by harmful factors, leading to localized erosions in the stomach or proximal duodenum. The main causes are Helicobacter pylori infection and chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs).Helicobacter pylori–Induced InjuryBacterial Adaptation and Colonization:H. pylori is a spiral, Gram-negative bacterium adapted to the acidic stomach. and transmitted through oral-oral or...
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Peptic Ulcer Disease II: Pathophysiology01:28

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Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
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Related Experiment Video

Updated: May 3, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Ulcerative lichen planus in childhood.

Chiyadu Padmini1, K Yellamma Bai2, Vinil Chaitanya3

  • 1Department of Pedodontics and Preventive Dentistry, Malla Reddy Institute of Dental Sciences, Suraram, Zediametla, Hyderabad 500055, Andhra Pradesh, India.

Case Reports in Dentistry
|January 24, 2014
PubMed
Summary

This study reports a rare case of ulcerative oral lichen planus in a 12-year-old boy. Prompt diagnosis and local treatment led to a positive outcome, highlighting the need for considering this condition in pediatric oral lesions.

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Area of Science:

  • Oral Medicine
  • Dermatology
  • Pediatric Dentistry

Background:

  • Lichen planus (LP) is a chronic inflammatory condition affecting skin and mucous membranes.
  • While common in adults, pediatric LP, especially oral ulcerative forms, is rarely documented.

Purpose of the Study:

  • To report an unusual case of ulcerative oral lichen planus on the tongue dorsum in a 12-year-old boy.
  • To emphasize the importance of considering LP in the differential diagnosis of pediatric oral ulcerative lesions.

Main Methods:

  • Clinical examination of a 12-year-old boy presenting with a painful, burning oral lesion.
  • Histopathological analysis to confirm the diagnosis of ulcerative oral lichen planus.
  • Institution of localized treatment for the oral lesion.

Main Results:

  • A white ulcerative lesion was identified on the dorsum of the tongue.
  • Diagnosis of ulcerative oral lichen planus was confirmed through clinical and histopathological findings.
  • The patient showed a favorable response to the instituted local treatment.

Conclusions:

  • Pediatric ulcerative oral lichen planus, though rare, should be considered in the differential diagnosis of oral mucosal lesions in children.
  • Early diagnosis and appropriate local management can lead to effective treatment outcomes in pediatric LP cases.