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Acute pancreatitis induced by anticancer chemotherapy
W Ben Kridis1, A Khanfir2, M Frikha2
1Department of Oncology, Habib Bourguiba Hospital, Sfax 3029, Tunisia. walabenkridis@yahoo.fr
Acta Clinica Belgica
|January 25, 2014
Summary
Drug-induced pancreatitis is a rare side effect. This case highlights that chemotherapy drugs, like ifosfamide and doxorubicin, can cause acute pancreatitis in neurosarcoma patients.
Area of Science:
- Oncology
- Gastroenterology
- Pharmacology
Background:
- Drug-induced pancreatitis is an uncommon adverse event, occurring in 1.4-2% of cases.
- Neurosarcoma is a rare malignant tumor, often requiring aggressive chemotherapy regimens.
Observation:
- A 20-year-old female patient with abdominal wall neurosarcoma developed acute pancreatitis.
- The patient was undergoing treatment with a combination regimen of ifosfamide and doxorubicin.
Findings:
- Chemotherapy-induced acute pancreatitis is a rare but significant complication.
- The ifosfamide and doxorubicin regimen was implicated in the development of pancreatitis.
Implications:
- Clinicians should consider chemotherapeutic agents as a potential cause of acute pancreatitis in patients with gastrointestinal symptoms.
- Early recognition and management of drug-induced pancreatitis are crucial for patient outcomes in oncology.
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