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Updated: May 3, 2026

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
Published on: November 25, 2015
Programmable redox state of the nickel ion chain in DNA
Hsueh-Liang Chu1, Shao-Chien Chiu, Ching-Feng Sung
1Department of Biological Science and Technology, National Chiao Tung University , 75 Bo Ai Street, Hsinchu, Taiwan , 30068.
Abstract:
DNA is a nanowire in nature which chelates Ni ions and forms a conducting chain in its base-pairs (Ni-DNA). Each Ni ion in Ni-DNA exhibits low (Ni(2+)) or high (Ni(3+)) oxidation state and can be switched sequentially by applying bias voltage with different polarities and writing times. The ratio of low and high oxidation states of Ni ions in Ni-DNA represents a programmable multistate memory system with an added capacitive component, in which multistate information can be written, read, and erased. This study also indicates that the biomolecule-based self-organized nanostructure can be used as a template for nanodevice fabrication.
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