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Impulsiveness in chronic hepatitis C patients

Bruno Cópio Fábregas1, Mery Natali Silva Abreu2, Aieska Kellen Dantas Dos Santos2

  • 1Neuropsychiatry Group, Neurology Division, University Hospital, Universidade Federal de Minas Gerais, 30130-100 Belo Horizonte, MG., Brazil; Infectious Diseases Reference Center-CTR-DIP Orestes Diniz, Municipal Health Division/Universidade Federal de Minas Gerais, 30150-260 Belo Horizonte, MG., Brazil; Tropical Medicine Program, School of Medicine, Universidade Federal de Minas Gerais, Belo 30130-100 Horizonte, MG., Brazil.

General Hospital Psychiatry
|January 25, 2014
PubMed

Insights

Impulsiveness is common in chronic hepatitis C (CHC) patients and linked to various mental health issues. Managing impulsivity is crucial for effective CHC patient care.

Area of Science:

  • Psychiatry
  • Hepatology
  • Clinical Psychology

Background:

  • Chronic hepatitis C (CHC) is a significant global health concern.
  • Understanding the psychological profile of CHC patients is vital for comprehensive care.
  • Impulsivity is a complex trait that may impact treatment adherence and outcomes.

Purpose of the Study:

  • To investigate the prevalence of impulsiveness in CHC patients.
  • To identify sociodemographic, clinical, and psychopathological factors associated with impulsiveness in this population.

Main Methods:

  • A cross-sectional study involving 91 CHC patients at a Brazilian infectious diseases outpatient service.
  • Assessment using the Barrat Impulsiveness Scale (BIS), Brief Fatigue Inventory, Beck Depression Inventory, and Hamilton Anxiety Scale.
  • Psychiatric evaluation using the Mini International Neuropsychiatric Interview and multivariate regression analysis.

Main Results:

  • The mean total impulsiveness score (BIS) was 64.6±9.8.
  • Impulsiveness was associated with lower educational attainment, current interferon-α (IFN) use, and several psychiatric disorders including ADHD, alcohol use disorder, mixed anxiety and depressive disorder, specific phobia, and bipolar spectrum disorders.
  • Anxiety symptoms and suicide risk were also linked to impulsiveness, particularly during IFN treatment.

Conclusions:

  • Impulsiveness is a frequent characteristic among CHC patients.
  • A strong association exists between impulsiveness and various psychopathological conditions in CHC patients.
  • Clinical management of CHC patients should incorporate strategies to address impulsivity.
Abstract

Keywords:
Chronic hepatitis CImpulsive behaviorInterferon-αMental health

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