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Verruciform xanthoma.

Bartley J Gill¹, Audrey J Chan, Sylvia Hsu

¹Baylor College of Medicine.

Dermatology Online Journal

|January 25, 2014

Summary

This summary is machine-generated.

A polypoid papule on the scrotum was diagnosed as verruciform xanthoma. This rare condition involves a buildup of foamy macrophages in the skin biopsy.

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Area of Science:

Dermatopathology
Histopathology
Cutaneous Oncology

Background:

Verruciform xanthoma is a rare, benign oral and cutaneous condition.
It typically presents as a solitary papule or plaque.
Differential diagnosis includes various benign and malignant epithelial and connective tissue neoplasms.

Observation:

A 50-year-old male presented with a several-month history of a scrotal polypoid papule.
Physical examination revealed a solitary, exophytic lesion on the scrotum.

Findings:

Histopathological examination of the biopsy specimen showed a dense accumulation of macrophages with foamy cytoplasm.
These findings are characteristic of verruciform xanthoma.
No significant atypia or malignancy was identified.

Implications:

This case highlights the importance of considering verruciform xanthoma in the differential diagnosis of scrotal papules.
Accurate histopathological diagnosis is crucial for appropriate management and patient reassurance.
Further research into the etiology and specific treatment protocols for cutaneous verruciform xanthoma is warranted.