Related Experiment Video
Updated: May 3, 2026
Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Topography-based keratoconus progression after corneal collagen crosslinking
George D Kymionis1, Alexandra E Karavitaki, Michael A Grentzelos
1*Vardinoyiannion Eye Institute of Crete (VEIC), Faculty of Medicine, University of Crete, Heraklion, Greece; and †Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL.
Purpose:
The aim of this study was to report 2 cases with topographic keratoconus progression despite stability for a long-term period after corneal collagen crosslinking (CXL).
Methods:
This is a case report.
Results:
Two patients with progressive keratoconus underwent CXL treatment. Four and 5 years postoperatively, a topographic examination revealed an increase in the keratometric values indicating keratoconus progression.
Conclusions:
Post-CXL, topographic keratoconus progression may occur several years after, despite stability for a long-term period.
