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Updated: May 3, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Stabilized porous liposomes with encapsulated Gd-labeled dextran as a highly efficient MRI contrast agent
Zhiliang Cheng1, Ajlan Al Zaki, Ian W Jones
1Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. zcheng@seas.upenn.edu.
Abstract:
A highly efficient contrast agent for magnetic resonance imaging was developed by encapsulating gadolinium within a stabilized porous liposome. The highly porous membrane leads to a high relaxivity of the encapsulated Gd. The stability of the liposome was improved by forming a polymer network within the bilayer membrane.
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