Related Experiment Video
Updated: May 3, 2026
Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
A minimally invasive technique for occluding large muscular ventricular septal defects in infants
Zibo Gao1, Qin Wu, Tianli Zhao
1Department of Thoracic and Cardiovascular Surgery, The Second Hospital of Centre South University, Changsha, PR China.
Objective:
This study investigated the feasibility, timing and indications for closure of large muscular ventricular septal defects (VSDs) in infants without use of a cardiopulmonary bypass.
Methods:
A total of 9 infants with large muscular VSDs ranging in size from 7 to 15 mm were treated by minimally invasive closure without cardiopulmonary bypass between April 2010 and February 2013.
Results:
All surgeries were successful without resulting in uncontrolled systemic infection, a pulmonary hypertensive crisis or a severely low cardiac output, and with an apparently shorter operation time and postoperative tracheal cannula.
Conclusions:
VSD closure without cardiopulmonary bypass can improve the efficacy and prognosis of infants with large muscular VSDs and concurrent pulmonary infections or respiratory failure.
