Multiple interferon subtypes: the phenomenon and its relevance

M Rubinstein1

  • 1Department of Virology, Weizmann Institute of Science, Rehovot, Israel.

Journal of Interferon Research
|October 1, 1987
PubMed

Over the last 10 years the structure of various human interferon-alpha (IFN-alpha) and interferon-gamma (IFN-gamma) subtypes was elucidated by combining protein chemistry and molecular biology. In this article some key studies related to the interferon structure are reviewed. The significance of the multiplicity of IFN-alpha and IFN-gamma subtypes is discussed in view of some current results.