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Cisplatin-induced gastric paresis.
1Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104.
Journal of Neuro-Oncology
|January 1, 1987
Summary
This case study details a patient with testicular carcinoma who experienced severe nausea, vomiting, and peripheral neuropathy after cisplatin chemotherapy. These symptoms suggest a rare instance of cisplatin-induced gastric autonomic neuropathy.
Area of Science:
- Oncology
- Neuroscience
- Pharmacology
Background:
- Metastatic testicular carcinoma is a complex malignancy requiring aggressive treatment.
- Cisplatin-based chemotherapy, including the PVB regimen (cisplatin, vinblastine, bleomycin), is a standard treatment for testicular cancer.
- Chemotherapy can induce various toxicities, including peripheral neuropathy and gastrointestinal distress.