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Cellular basis of memory for addiction

Eric J Nestler1

  • 1Fishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, USA.

Dialogues in Clinical Neuroscience
|January 25, 2014
PubMed
Summary

Drug addiction stems from biological changes in the brain, leading to compulsive drug seeking. Understanding these molecular and cellular adaptations, akin to memory, is key to developing new treatments.

Keywords:
CREBdendritic spinesepigeneticsgene transcriptionnucleus accumbenssynaptic plasticityventral tegmental areawhole cell plasticityΔFosB

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