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The cellular target specificity of pateamine A

James H Matthews1, David R Maass1, Peter T Northcote1

  • 1Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

Zeitschrift Fur Naturforschung. C, Journal of Biosciences
|January 28, 2014
PubMed
Summary

Pateamine A, a natural compound, inhibits eukaryotic initiation factor 4A (eIF4A) and affects cell division. While it also impacts actin and tubulin, these are not its primary cellular targets.

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