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Updated: May 3, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Abolition of lifelong specific phobia: a novel therapeutic consequence of left mesial temporal lobectomy
1a Brighton and Sussex University Hospitals NHS Trust, Royal Sussex County Hospital , Eastern Road, Brighton , BN2 5BE , UK.
Abstract:
Numerous imaging studies have confirmed the amygdala as prominent within a neural network mediating specific phobia, including arachnophobia. We report the case of a patient in whom arachnophobia was abolished after left temporal mesial lobectomy, with unchanged fear responses to other stimuli. The phenomenon of abolition of specific phobia after amygdala removal has not, to our knowledge, been previously reported.
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