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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids

Ivana Košiová1, Ondřej Šimák1, Natalya Panova1

  • 1Institute of Organic Chemistry and Biochemistry, Academy of Sciences v. v. i., Flemingovo 2, 166 10 Prague 6, Czech Republic.

European Journal of Medicinal Chemistry
|January 28, 2014
PubMed

Keywords:
Bi-substrate-like inhibitorConformationally constrained nucleotide analogHuman thymidine phosphorylaseMichael additionPBMCPhosphonate

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