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Updated: May 3, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic
Jing Xu1, Cheng-shi Jiang2, Zai-long Zhang3
11] College of Science, China University of Petroleum, Qingdao 266580, China [2] Weifang Biomedical Innovation and Entrepreneurship Service Center, Weifang 261205, China.
Abstract:
Macrolides, which comprise a family of lactones with different ring sizes, belong to the polyketide class of natural products. Resorcinolic macrolides, an important subgroup, possess interesting structures and exhibit a wide variety of bioactivities, such as anti-tumor, anti-bacteria, and anti-malaria activities, etc. This review summarizes progress in isolation, bioactivity studies, biosynthesis, and representative chemical syntheses of this group of macrolides in recent decades, encompassing 63 naturally occurring macrolides published in 120 articles.
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