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Updated: May 3, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
D-dimer value more than 3.6 μg/ml is highly possible existence deep vein thrombosis
Shinichi Nata1, Shinichi Hiromatsu, Yusuke Shintani
1Department of Surgery, Kurume University School of Medicine.
Objective:
The present study aimed to establish whether a more optimal cutoff value for D-dimer testing could definitively rule out acute deep vein thrombosis (DVT).
Methods:
Between April 2009 and March 2010, 190 referral patients suspected to have DVT were assessed by the D-dimer assay. Additionally, ultrasonography (US) and computed tomography (CT) imaging were performed to detect thrombosis.
Results:
DVT was identified in 47 patients (24%). The average D-dimer level in patients with DVT was 17.6±22.4 μg/ml, and was significantly lower (p=0.035),] at 2.7±4.2 μg/ml, in those without DVT. On the basis of receiver operating curve analysis, the specificity of the D-dimer for diagnosing DVT increased from 40% to 78.3%, and its sensitivity reached 93.8%, when the cutoff value for the assay was set at 3.6 μg/ml.
Conclusions:
D-dimer value over 3.6 μg/ml was highly prognostic for DVT.
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Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...

