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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
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Breakthrough cancer pain: the current situation.

Alison Buchanan1, Andrew Davies2

  • 1Research Nurse in Palliative Care.

International Journal of Palliative Nursing
|January 28, 2014
PubMed
Summary

Breakthrough cancer pain (BTcP) significantly impacts daily life for patients with cancer. This paper details BTcP

Area of Science:

  • Oncology
  • Pain Management
  • Palliative Care

Background:

  • Breakthrough cancer pain (BTcP) is a prevalent issue in oncology care.
  • BTcP significantly impairs patients' quality of life and daily functioning.
  • Understanding BTcP's characteristics is crucial for effective management.

Purpose of the Study:

  • To elucidate the clinical features of breakthrough cancer pain (BTcP).
  • To assess the impact of BTcP on patients' activities of daily living.
  • To outline the fundamental principles of BTcP management and identify current challenges.

Main Methods:

  • Literature review of clinical features and patient-reported outcomes.
  • Analysis of existing management strategies and guidelines.

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  • Identification of challenges in current BTcP treatment.

    • Main Results:

    • Detailed description of BTcP's clinical presentation and variability.
    • Evidence of significant negative effects on patient mobility, social interaction, and emotional well-being.
    • Identification of gaps and difficulties in current BTcP management protocols.

    Conclusions:

    • BTcP presents unique challenges requiring specific management approaches.
    • Effective BTcP management necessitates addressing its distinct clinical features and impact.
    • Further research and refined strategies are needed to optimize BTcP care.