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Related Experiment Video

Updated: May 3, 2026

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Published on: November 26, 2019

Masticatory deficiency as a risk factor for cognitive dysfunction.

Francisco Bruno Teixeira¹, Luanna de Melo Pereira Fernandes², Patrycy Assis Tavares Noronha³

¹1. Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, 66075-900, Belém-Pará, Brazil;

International Journal of Medical Sciences

|January 28, 2014

Summary

Chewing supports cognitive functions, particularly memory and learning in the hippocampus. Masticatory deficiency is linked to dementia and spatial memory deficits, highlighting chewing's importance for brain health.

Keywords:

Chewing Cognition Hippocampus.Learning Masticatory Memory

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Area of Science:

Neuroscience
Cognitive Science
Gerontology

Background:

Chewing (mastication) plays a role in maintaining cognitive functions, especially in the hippocampus, a key area for memory and learning.
Masticatory deficiency, or impaired chewing ability, is increasingly associated with cognitive decline, including dementia and spatial memory deficits, particularly in aging populations.

Purpose of the Study:

To review current research on the impact of masticatory impairment on cognitive functions.
To explore the underlying mechanisms connecting chewing ability to cognitive performance in both animal models and human studies.

Main Methods:

Literature review of experimental animal studies and human epidemiological data.
Analysis of studies investigating the relationship between masticatory function and cognitive performance.

Main Results:

Evidence suggests a link between impaired chewing and deficits in cognitive functions, including spatial memory.
Epidemiological data indicate a correlation between masticatory deficiency and an increased risk or presence of Alzheimer's disease.

Conclusions:

Chewing is crucial for maintaining cognitive abilities and may play a protective role against cognitive decline.
Further research into the mechanisms underlying the chewing-cognition link could inform strategies for preventing or mitigating dementia.