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[Rhabdomyolysis as an unspecyfic symptom of mushroom poisoning--a case report]
1Oddział Chorób Wewnetrznych, Wojewódzkiego Szpitala Specjalistycznego w Białej Podlaskiej. pchwaluk@poczta.fm
Abstract:
Since 2001 a number of cases of mushroom poisoning with concomitant rhabdomyolysis have been described. Among the edible mushrooms growing in Europe, these reports concerned only Tricholoma equestre. The results of animal studies suggest that rhabdomyolysis could be a consequence of consumption of other edible fungi, and its occurrence depends on the amount of ingested mushrooms and individual sensitivity. To the best of our knowledge, this is the first report of rhabdomyolysis associated with the consumption of edible mushrooms from Leccinum and Boletus species. A 57-years old man was admitted to the hospital due to severe pain and weakness of thigh muscles with a high serum creatine kinase activity -3811 U/L. Within two days before hospitalization he consumed repeatedly large quantities of stewed Leccinum and Boletus mushrooms. Clinical signs of toxicity and biochemical changes subsided after several days of hospitalization. Rhabdomyolysis after ingestion of a large amount of mushrooms can be an unspecific symptom, unrelated to fungi species.
Insights
This study reports the first case of rhabdomyolysis linked to consuming Leccinum and Boletus mushrooms. Large quantities of edible mushrooms can potentially cause this muscle-damaging condition, regardless of species.
Area of Science:
- Toxicology
- Mycology
- Clinical Medicine
Background:
- Rhabdomyolysis cases linked to mushroom poisoning have primarily involved Tricholoma equestre.
- Animal studies suggest other edible fungi may also induce rhabdomyolysis, dependent on dosage and individual susceptibility.
Observation:
- A 57-year-old man presented with severe thigh muscle pain and weakness, and elevated serum creatine kinase (3811 U/L).
- The patient had consumed large quantities of stewed Leccinum and Boletus mushrooms two days prior to admission.
Findings:
- This case represents the first documented instance of rhabdomyolysis associated with the consumption of Leccinum and Boletus species.
- The patient's clinical signs and biochemical markers resolved within days of hospitalization.
Implications:
- Ingesting large amounts of edible mushrooms can potentially lead to rhabdomyolysis as a non-specific symptom.
- Fungi species may not be the sole determinant of rhabdomyolysis; quantity and individual factors are crucial.
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