Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Quarrying of Stone01:15

Quarrying of Stone

855
Quarrying is the process of extracting stone from a quarry, where specialized techniques are employed to remove large blocks of stone safely and efficiently. This process can involve controlled explosions or more precision-oriented methods such as cutting and drilling.
One common method involves using a diamond belt saw to cut large blocks from the quarry face. These blocks can be about 50 feet long and 12 feet high. After the initial vertical cut, drilling is performed at the base of the...
855
Acid Mine Drainage01:19

Acid Mine Drainage

112
Mining activities that disturb sulfide-rich rocks, particularly those containing pyrite (FeS₂), initiate a cascade of geochemical and microbiological processes with serious environmental implications. When exposed to air and water, pyrite undergoes oxidation, releasing sulfate, ultimately forming sulfuric acid and mobilizing heavy metals into surrounding water systems. This phenomenon, known as acid mine drainage (AMD), results in low pH waters laden with toxic elements that threaten...
112
Flail Chest-I01:24

Flail Chest-I

1.2K
Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
1.2K
Robbers Cave04:49

Robbers Cave

13.5K
During the 1950s, the landmark Robbers Cave experiment demonstrated that when groups must compete with one another, intergroup conflict, hostility, and even violence may result. At the Oklahoman summer camp, two troops of boys—termed the Rattlers and the Eagles—took part in a week-long tournament. During this time, their negativity culminated in derogatory name-calling, fistfights, and even vandalism and destruction of property. However, this work also revealed that such tension...
13.5K
Major Losses in Pipes01:28

Major Losses in Pipes

2.1K
When a fluid flows through a pipe, it experiences energy losses due to frictional resistance along the pipe walls, known as major losses. These energy losses result in a pressure drop, which varies based on the flow conditions — whether laminar or turbulent — and the specific physical properties of the fluid and pipe.
Fluid flow can be classified as laminar or turbulent, primarily based on the Reynolds number. This dimensionless number reflects the relative influence of inertial to...
2.1K
Thoracic Aorta01:15

Thoracic Aorta

2.5K
The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cryogenic Gas-phase IR Spectroscopy on a Commercial Ion Mobility-Mass Spectrometry Platform.

Analytical chemistry·2026
Same author

Cryogenic Gas-Phase Infrared Ion Spectroscopy of Ultraviolet-Induced Nucleotide Photoproducts.

Analytical chemistry·2025
Same author

A highly sensitive protein-RNA cross-linking mass spectrometry workflow with enhanced structural modeling potential.

Nucleic acids research·2025
Same author

The Road Toward Nanopore Sequencing of Glycosaminoglycans.

Handbook of experimental pharmacology·2025
Same author

Ion Mobility Mass Spectrometry-Based Disaccharide Analysis of Glycosaminoglycans.

Chemistry (Weinheim an der Bergstrasse, Germany)·2024
Same author

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.

Nature communications·2024

Related Experiment Video

Updated: May 3, 2026

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
08:33

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm

Published on: August 24, 2019

7.2K

Smaug destroys a huge treasure.

Michael Götze, Elmar Wahle

    Genome Biology
    |January 29, 2014
    PubMed
    Summary

    Smaug protein regulates maternal messenger RNAs (mRNAs) crucial for early fruit fly development. It controls translation and mRNA decay, impacting a large number of developmental genes.

    Area of Science:

    • Developmental Biology
    • Molecular Biology
    • Genetics

    Background:

    • Maternal mRNAs are essential for initiating embryonic development in many species.
    • Post-transcriptional regulation plays a critical role in controlling gene expression during early embryogenesis.

    Purpose of the Study:

    • To investigate the function of Smaug protein in regulating maternal mRNAs during early Drosophila development.
    • To identify the scope of Smaug's regulatory targets and its impact on developmental processes.

    Main Methods:

    • Utilized RNA sequencing (RNA-seq) to profile mRNA populations.
    • Employed genetic manipulation techniques to alter Smaug protein levels.
    • Performed functional assays to assess translation and mRNA decay rates.

    More Related Videos

    Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery
    07:12

    Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery

    Published on: April 8, 2021

    5.3K
    Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
    06:50

    Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

    Published on: December 24, 2013

    28.8K

    Related Experiment Videos

    Last Updated: May 3, 2026

    Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
    08:33

    Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm

    Published on: August 24, 2019

    7.2K
    Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery
    07:12

    Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery

    Published on: April 8, 2021

    5.3K
    Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
    06:50

    Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

    Published on: December 24, 2013

    28.8K

    Main Results:

    • Smaug protein was found to repress translation and induce mRNA decay for a significant number of maternal mRNAs.
    • A large set of maternal transcripts critical for early Drosophila development were identified as Smaug targets.
    • Smaug's activity directly influences the precise temporal control of gene expression required for embryogenesis.

    Conclusions:

    • Smaug is a key regulator of maternal mRNA metabolism, essential for orchestrating early development in Drosophila.
    • The findings reveal a broader role for Smaug than previously appreciated, highlighting its importance in controlling developmental trajectories.