Related Experiment Video
Updated: May 3, 2026
Microsurgical Venous Pouch Arterial-Bifurcation Aneurysms in the Rabbit Model: Technical Aspects
Published on: May 11, 2011
Investigating the clinical significance of mesh peritonization in abdominal vault suspension surgery using a
Hakan Nazik1, Mehmet Ali Narin1, Raziye Narin1
1Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, Adana, Turkey.
Objective:
To investigate the clinical significance of mesh peritonization in an experimental rabbit model.
Study Design:
Twenty rabbits were randomly assigned to two groups. A sacrouteropexy operation was performed in both groups using a polypropylene mesh. In the first group, the pelvic peritoneum was not closed over the mesh, and in the second group, the mesh was buried throughout the pelvic retroperitoneal tunnel. One month after mesh implantation, the abdomen was opened and the previous surgical site was explored. The primary outcome was intraabdominal adhesion formation; the secondary outcome was the histologic degree of tissue remodeling.
Results:
There were no statistically significant differences between the two groups in terms of adhesion scores and collagen organization (P=0.692, P=0.097, respectively). There was a greater degree of inflammation in the second group as identified by significantly higher scores for eosinophils-neutrophils, macrophages-foreign body giant cells and mononuclear cells (P=0.002, P=0.001 and P=0.002, respectively).
Conclusions:
Similar adhesion and collagen organization patterns were found in both groups, but indicators of the inflammatory process were significantly higher in the second group.
