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Related Experiment Video

Updated: May 3, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
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Intraoperative radiological margin assessment in breast-conserving surgery.

T Ihrai1, D Quaranta1, Y Fouche1

  • 1Centre Antoine Lacassagne, Breast Cancer and Reconstructive Surgery Unit, France.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|January 29, 2014
PubMed
Summary
This summary is machine-generated.

Intraoperative specimen radiography (IOSR) accurately assesses surgical margins during breast-conserving surgery. This X-ray technique can help achieve negative margins in 93.5% of cases, saving time and costs.

Keywords:
Breast cancerFaxitronIntraoperative histological examinationIntraoperative specimen radiographyMammogramsMargins status

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Area of Science:

  • Surgical Oncology
  • Radiology
  • Breast Cancer Management

Background:

  • Accurate margin assessment is critical in breast-conserving surgery to minimize recurrence.
  • Intraoperative margin evaluation can reduce reoperation rates.
  • Traditional margin assessment relies on final histology, delaying results.

Purpose of the Study:

  • To evaluate the accuracy of intraoperative specimen radiography (IOSR) for margin assessment in breast-conserving surgery.
  • To determine the potential impact of IOSR on achieving negative margins.
  • To assess the time and economic implications of using IOSR.

Main Methods:

  • A prospective study included 170 patients with visible lesions on preoperative mammograms.
  • Intraoperative X-ray of lumpectomy specimens was performed for margin assessment.
  • Final histological data were collected to compare with IOSR findings.

Main Results:

  • IOSR enabled margin status evaluation in 91.2% of specimens (155 cases).
  • If margin assessment relied solely on IOSR, the positive margin rate would have been 6.5%.
  • The study suggests negative margins could have been achieved in 93.5% of cases using IOSR.

Conclusions:

  • Intraoperative specimen radiography is an accurate tool for margin assessment in breast-conserving surgery.
  • Utilizing IOSR can significantly increase the rate of achieving negative surgical margins.
  • This technique offers potential time savings and substantial economic benefits in breast cancer treatment.