Related Experiment Video
Updated: May 3, 2026

Use of 3D Robotic Ultrasound for In Vivo Analysis of Mouse Kidneys
Published on: August 12, 2021
A novel 3-dimensional image analysis system for case-specific kidney anatomy and surgical simulation to facilitate
Yoshinobu Komai1, Yasuyuki Sakai1, Naoto Gotohda2
1Department of Urology, National Cancer Center Hospital East, Chiba, Japan.
Objective:
To report our initial experience with the novel 3-dimensional (3D) image analysis system Synapse Vincent in clampless partial nephrectomy (PN), describing its advantages with regard to short-term surgical outcomes and its usefulness as an informed consent tool.
Methods:
Twenty-six patients with renal cell carcinoma underwent clampless PN navigated with the aid of case-specific 3D anatomic video images of the kidney, after surgical simulation using the same video system. Baseline characteristics were reviewed, and short-term surgical outcomes were recorded. Of the 26, 6 had imperative indications, and 22 were treated with a minimally invasive approach. Before tumor excision, the renal hilar vessels were meticulously dissected, and definite tumor feeders were selectively ligated. Before patients consented to PN, the surgical procedure and perioperative risks were explained to each patient using case-specific 3D video images; subsequently, surgeons asked patients whether the 3D images had helped them understand PN more clearly than 2D images would have.
Results:
All operations were successfully completed without clamping, with negative surgical margins. No patients required blood transfusions. During PN, the surgeons confirmed the accuracy of the reconstructed 3D images and surgical simulations in all cases. All patients answered that the 3D images had helped them understand their disease status and surgical risks.
Conclusion:
This is the first report on the Synapse Vincent 3D image analysis system for kidney surgery. Its 3D images and surgical simulation helped not only surgeons in their performance of clampless PN but also patients in their understanding of the operation.
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Imaging Studies I: Kidney, Ureter, and Bladder Studies
Imaging Studies III: Computed Tomography

