Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Expression at Multiple Steps01:23

Regulation of Expression at Multiple Steps

1.4K
The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the...
1.4K
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

20.2K
Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
20.2K
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

3.1K
3.1K
What is Gene Expression?01:42

What is Gene Expression?

132.7K
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
132.7K
What is Gene Expression?01:36

What is Gene Expression?

10.1K
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then...
10.1K
What is Gene Expression?01:42

What is Gene Expression?

18.7K
18.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering transgenerational epigenetic inheritance in mammals.

Nature reviews. Genetics·2023
Same author

Optical filament recording of cellular events.

Nature reviews. Genetics·2023
Same author

New cuts for CRISPR effectors.

Nature reviews. Genetics·2022
Same author

Viral protection from viruses.

Nature reviews. Genetics·2022
Same author

A TAD refined for gene regulation.

Nature reviews. Genetics·2022
Same author

RADARs and READRs for programmable RNA sensing.

Nature reviews. Genetics·2022

Related Experiment Video

Updated: May 3, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

23.3K

Gene regulation: Characterizing monoallelic expression

Darren J Burgess

    Nature Reviews. Genetics
    |January 29, 2014
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells
    11:31

    Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells

    Published on: April 2, 2016

    12.4K
    Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish
    11:42

    Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish

    Published on: October 27, 2017

    10.5K

    Related Experiment Videos

    Last Updated: May 3, 2026

    An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
    10:17

    An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

    Published on: November 3, 2010

    23.3K
    Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells
    11:31

    Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells

    Published on: April 2, 2016

    12.4K
    Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish
    11:42

    Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish

    Published on: October 27, 2017

    10.5K