Intrauterine Drug Delivery Systems
Teratogenicity
Regression Toward the Mean
Gonadal and Placental Hormones
Prodrugs
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F Fuchs1, F Audibert2, M-V Senat3
1Département de gynécologie-obstétrique, CHU Sainte-Justine, 3175, chemin de la Côte-Sainte-Catherine, Montréal H3T 1C5, Québec, Canada; Inserm, CESP Centre de recherche en épidémiologie et santé des populations, U1018, reproduction et développement de l'enfant, hôpital du Kremlin-Bicêtre, secteur bleu - Pierre-Lajaunias, porte 89, 82, rue du Général-Leclerc, 94276 Le Kremlin-Bicêtre cedex, France; Université Paris-Sud, UMRS 1018, hôpital du Kremlin-Bicêtre, 82, rue du Général-Leclerc, 94276 Le Kremlin-Bicêtre cedex, France.
Progesterone effectively prevents preterm birth in specific high-risk pregnancies, including those with short cervix or prior preterm birth. Its use should be restricted to these indications and research protocols for other conditions.
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