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Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

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Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
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Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
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The International Spinal Cord Injury Pain Basic Data Set (version 2.0).

E Widerström-Noga1, F Biering-Sørensen2, T N Bryce3

  • 11] Miami Project to Cure Paralysis, Lois Pope Life Center, Miller School of Medicine, University of Miami, Miami, FL, USA [2] Department of Rehabilitation Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA.

Spinal Cord
|January 29, 2014
PubMed
Summary
This summary is machine-generated.

The International Spinal Cord Injury Pain Basic Data Set (ISCIPBDS) was revised to version 2.0, simplifying core questions for spinal cord injury (SCI) pain assessment. This updated tool enhances clinical relevance and research utility for SCI pain management.

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Area of Science:

  • Neurology
  • Pain Medicine
  • Rehabilitation Medicine

Background:

  • Spinal cord injury (SCI) pain is a complex challenge impacting patient quality of life.
  • Existing data sets for SCI pain require updates to reflect current clinical understanding and research advancements.
  • Standardized data collection is crucial for effective SCI pain research and treatment.

Purpose of the Study:

  • To revise the International Spinal Cord Injury Pain Basic Data Set (ISCIPBDS) incorporating new developments and community feedback.
  • To create a more concise yet clinically relevant tool for assessing SCI-related pain.
  • To improve the utility of the ISCIPBDS for both clinical practice and research.

Main Methods:

  • An international working group evaluated suggestions and developments in SCI pain.
  • The International Spinal Cord Injury Pain Basic Data Set (ISCIPBDS) underwent modifications, resulting in version 2.0.
  • The revised data set was extensively reviewed by leading SCI and pain organizations and experts.

Main Results:

  • The revised ISCIPBDS (version 2.0) is significantly shortened while retaining essential questions on SCI-related pain.
  • Key revisions include an updated SCI pain classification and the omission of specific temporal pain pattern and pain interference questions.
  • The remaining pain interference questions focus on overall impact on activities, mood, and sleep, using a 0-10 scale.

Conclusions:

  • The revised ISCIPBDS (version 2.0) offers a streamlined and effective instrument for SCI pain assessment.
  • This updated data set supports standardized data collection for improved SCI pain research and clinical management.
  • The revisions ensure the ISCIPBDS remains a valuable tool for the global SCI and pain community.