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Updated: May 3, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Ad hoc cost analysis of the new gastrointestinal bleeding algorithm in patients with ventricular assist device
Hitoshi Hirose1, Konrad Sarosiek, Nicholas C Cavarocchi
1From the Department of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania.
Insights
A new deep bowel enteroscopy algorithm for gastrointestinal bleeding (GIB) in ventricular assist device (VAD) patients significantly reduces procedures, transfusions, and costs compared to traditional methods.
Area of Science:
- Cardiovascular Surgery
- Gastroenterology
- Medical Device Technology
Background:
- Gastrointestinal bleeding (GIB) is a frequent complication in patients with nonpulsatile ventricular assist devices (VAD).
- Previous research highlighted the need for improved diagnostic and management strategies for GIB in this patient population.
Purpose of the Study:
- To evaluate a novel algorithm utilizing deep bowel enteroscopy for the workup of GIB in VAD patients.
- To compare the efficacy, resource utilization, and cost-effectiveness of the new algorithm against traditional GIB workup protocols.
Main Methods:
- Implementation of a new diagnostic algorithm centered on deep bowel enteroscopy for GIB in VAD patients.
- Comparison of patient outcomes, including procedure frequency, transfusion requirements, and diagnostic time, between the new algorithm group and a historical control group undergoing traditional GIB workup.
Main Results:
- The new algorithm group experienced fewer diagnostic procedures and required fewer transfusions compared to the traditional group.
- Diagnosis of GIB was achieved more rapidly with the new algorithm.
- Significant cost savings were observed, with procedure charges averaging ~$2,902 per episode in the new algorithm group versus ~$9,013 in the traditional group (p < 0.0001).
Conclusions:
- The novel deep bowel enteroscopy algorithm offers a more efficient and cost-effective approach to managing GIB in VAD patients.
- This strategy leads to reduced healthcare resource utilization, including fewer transfusions and diagnostic tests, while achieving substantial cost savings per bleeding episode.
Abstract:
Gastrointestinal bleed (GIB) is a known complication in patients receiving nonpulsatile ventricular assist devices (VAD). Previously, we reported a new algorithm for the workup of GIB in VAD patients using deep bowel enteroscopy. In this new algorithm, patients underwent fewer procedures, received less transfusions, and took less time to make the diagnosis than the traditional GIB algorithm group. Concurrently, we reviewed the cost-effectiveness of this new algorithm compared with the traditional workup. The procedure charges for the diagnosis and treatment of each episode of GIB was ~ $2,902 in the new algorithm group versus ~ $9,013 in the traditional algorithm group (p < 0.0001). Following the new algorithm in VAD patients with GIB resulted in fewer transfusions and diagnostic tests while attaining a substantial cost savings per episode of bleeding.

