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Serum calcium and protein in haemoglobin-SS patients
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1987
Insights
Serum calcium levels are significantly lower in individuals with haemoglobin SS disease. Conversely, total serum protein levels are notably higher in these patients compared to controls.
Area of Science:
- Biochemistry
- Hematology
- Clinical Chemistry
Background:
- Sickle cell disease (haemoglobin SS) is a genetic blood disorder.
- Electrolyte and protein imbalances are common in chronic diseases.
- Understanding these imbalances is crucial for patient management.
Purpose of the Study:
- To investigate serum calcium and total serum protein levels in haemoglobin SS patients.
- To compare these levels with a healthy control group.
Main Methods:
- Blood samples were collected from haemoglobin SS patients and a control group.
- Total serum calcium, total serum protein, and albumin levels were measured.
- Statistical analysis was performed to compare the groups.
Main Results:
- Haemoglobin SS patients exhibited significantly lower serum calcium levels.
- Total serum protein levels were significantly elevated in haemoglobin SS patients.
- Albumin levels were also assessed but not detailed in the provided abstract.
Conclusions:
- There are significant alterations in calcium and protein metabolism in haemoglobin SS disease.
- These findings may have implications for the pathophysiology and clinical care of sickle cell disease.
Abstract:
Total serum calcium, total serum protein and albumin were estimated in haemoglobin-SS patients. The same estimations were carried out on a control group consisting of subjects from the same locality and similar age ranges. It was observed that the serum calcium level was significantly lower in haemoglobin-SS patients while total serum protein was significantly elevated in these same patients.