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Published on: December 15, 2023
Abdominal cerebrospinal fluid pseudocyst: a comparative analysis between children and adults
Carlos B Dabdoub1, Carlos F Dabdoub, Mario Chavez
1Division of Neurosurgery, Japanese University Hospital, Av. Japón #50 y 30 Anillo Interno, Santa Cruz de la Sierra, Bolivia, carlosdabdoub@hotmail.com.
Insights
Abdominal cerebrospinal fluid (CSF) pseudocysts are rare complications of ventriculoperitoneal shunts (VPS). This study compares pediatric and adult cases, finding distinct trends in etiology, infection rates, and recurrence between the two groups.
Area of Science:
- Neurosurgery
- Pediatric Surgery
- Medical Complications
Background:
- Abdominal cerebrospinal fluid (CSF) pseudocysts are infrequent but significant complications following ventriculoperitoneal shunt (VPS) placement.
- Existing literature lacks comparative analyses between pediatric and adult populations experiencing this complication.
Purpose of the Study:
- To present institutional experience with abdominal CSF pseudocysts.
- To conduct a comparative analysis of abdominal CSF pseudocysts in children versus adults.
Main Methods:
- A comprehensive literature search of the PubMed database was conducted for reports from 1954 to 2012.
- Statistical comparisons were performed on clinical features, hydrocephalus etiology, shunt revision, CSF infection, treatment, and recurrence rates.
- Chi-square or Fisher's exact tests were utilized to assess variable associations.
Main Results:
- A total of 393 cases were analyzed (295 children, 55 adults).
- Children exhibited higher rates of positive CSF cultures (33%) compared to adults (15%), particularly those under 10 years.
- Recurrence rates were 19.8% in children and 24.2% in adults, with differing etiological factors between age groups.
Conclusions:
- Observed differences in etiology and treatment suggest distinct patterns between pediatric and adult abdominal CSF pseudocysts.
- Further well-designed cohort studies are recommended to validate these findings and inform clinical practice.
Purpose:
Abdominal cerebrospinal fluid (CSF) pseudocyst is a rare but important complication in patients with ventriculoperitoneal shunt (VPS). In addition to presenting our experience, we performed a comparative analysis between children and adults with this entity. To the author's knowledge, there are no studies in which this condition has been compared.
Methods:
The PubMed database was searched for all relevant reports published from 1954 to 2012. The differences were statistically compared, especially regarding clinical investigations, etiology of the hydrocephalus, shunt revision, CSF infection, treatment, and recurrence. Chi-square test or Fisher's exact test was used to find associations among the variables.
Results:
Compiled from literature, we found 393 cases of abdominal pseudocyst: 295 children, including our cases, and 55 adults, with age not informed in 43 cases. In children, 33 % of the patients have a positive culture on presentation, with higher incidence in children younger than 10 years. In contrast, only 15 % among adults were positive CSF culture. In total, 287 abdominal pseudocyst cases who underwent shunt revision have been reported; 78.4 % of children and 62.2 % of adults. The main occurrence of this complication according to the etiology of hydrocephalus in children was different from adults. The recurrence of pseudocyst occurred in 19.8 and 24.2 % of children and adults, respectively.
Conclusions:
The differences between children and adults might represent distinct trends on the etiology and treatment of this entity. Hence, additional well-designed cohort studies will be necessary to strengthen our findings.
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