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Salmonella typhimurium epidural empyema in an HIV-infected patient

Wissem Hachfi1, Foued Bellazreg1, Mohamed Ladib2

  • 1Department of Infectious Diseases, and Internal Medicine, Farhat Hached University Hospital;

Infectious Disease Reports
|January 29, 2014
PubMed

Insights

Salmonella typhimurium can cause rare intracranial infections, particularly in immunocompromised individuals. This case highlights successful treatment of a Salmonella epidural empyema with osteomyelitis using antibiotics and surgery.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Microbiology

Background:

  • Focal intracranial infections caused by Salmonella are uncommon.
  • Such infections predominantly affect immunocompromised patients.

Observation:

  • A 37-year-old human immunodeficiency virus (HIV)-positive male presented with a three-day history of headache, fever, and sweats.
  • Clinical examination revealed Salmonella typhimurium epidural empyema with adjacent frontal bone osteomyelitis.

Findings:

  • The patient was successfully treated with a combination of antibiotics and surgical drainage.
  • Prompt diagnosis and intervention led to a favorable outcome.

Implications:

  • This case underscores the importance of considering Salmonella in the differential diagnosis of intracranial infections in immunocompromised hosts.
  • Effective management involves a multidisciplinary approach including infectious disease specialists, neurosurgeons, and radiologists.
  • Early surgical intervention alongside appropriate antibiotic therapy is crucial for managing Salmonella epidural empyema and associated osteomyelitis.
Keywords:
Salmonella typhimuriumepidural empyemahuman immunodeficiency virus.

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