Related Experiment Video
Updated: May 3, 2026
Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
Published on: February 8, 2016
Is incidental recovery of yeast from enteric pathogen stool cultures obtained from hospitalized patients clinically
Rachel A Pfeifer1, Peter C Iwen2, Fang Qiu3
1The Nebraska Medical Center, Department of Pharmaceutical & Nutrition Care, Omaha, NE;
Abstract:
A matched case-control study was conducted to investigate gastrointestinal colonization with yeast as a predictor of invasive candidiasis (IC) in patients who underwent an enteric pathogen test. No significant association was detected between gastrointestinal colonization and IC. However, gastrointestinal colonization with yeast was associated with increased antimicrobial exposure and median length of hospitalization.
Insights
Gastrointestinal yeast colonization does not predict invasive candidiasis (IC). However, yeast in the gut is linked to more antibiotic use and longer hospital stays in patients tested for enteric pathogens.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Clinical Microbiology
Background:
- Invasive candidiasis (IC) is a serious bloodstream infection.
- Gastrointestinal (GI) yeast colonization is common in hospitalized patients.
- Predictors of IC, especially in patients undergoing enteric pathogen testing, require further investigation.
Observation:
- A matched case-control study analyzed patients tested for enteric pathogens.
- The study specifically examined the relationship between GI yeast colonization and subsequent IC.
- Data on antimicrobial exposure and hospitalization duration were also collected.
Findings:
- No statistically significant association was found between GI yeast colonization and the development of IC.
- GI yeast colonization was, however, significantly associated with increased exposure to antimicrobial agents.
- Patients with GI yeast colonization also experienced a longer median length of hospitalization.
Implications:
- GI yeast colonization may serve as a marker for patients with higher antimicrobial exposure and prolonged hospital stays.
- Current findings do not support using GI yeast colonization as a direct predictor for invasive candidiasis.
- Further research could explore the mechanisms linking GI yeast colonization to increased healthcare utilization.
More Related Videos
08:23Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
Published on: March 10, 2020
13:47Establishment of an In vitro System to Study Intracellular Behavior of Candida glabrata in Human THP-1 Macrophages
Published on: December 10, 2013
