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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

360
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Diphtheria01:28

Diphtheria

175
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
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Related Experiment Video

Updated: May 3, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
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Streptococcus dysgalactiae endocarditis presenting as acute endophthalmitis.

Angelina Su-Min Yong1, Su Yin Lau1, Tsung Han Woo1

  • 1Department of General Medicine, Flinders Medical Centre and Faculty of Health Science, Flinders University, Bedford Park, South Australia.

Infectious Disease Reports
|January 29, 2014
PubMed
Summary

Endogenous endophthalmitis, a rare eye infection, can be caused by Streptococcus dysgalactiae, often linked to infective endocarditis. This case highlights a rare presentation and successful multimodal treatment for improved vision.

Keywords:
EndocarditisGroup C streptococcusGroup G streptococcusendophthalmitisstreptococcus dysgalactiae.

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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Cardiology

Background:

  • Endogenous endophthalmitis is a severe intraocular infection with poor visual outcomes.
  • Infective endocarditis is the most common cause of endogenous endophthalmitis, typically involving Group A or B streptococci.

Observation:

  • This case report details a rare instance of endogenous endophthalmitis caused by Streptococcus dysgalactiae.
  • The endophthalmitis was the initial presentation of infective endocarditis, likely originating from osteomyelitis in a diabetic patient.

Findings:

  • Streptococcus dysgalactiae, a Group C/G streptococcus, is an uncommon pathogen in endocarditis-related endophthalmitis.
  • The patient received a comprehensive treatment including antibiotics, intravitreal injections, amputations, and valve replacement.

Implications:

  • This case expands the understanding of etiological agents in endocarditis-associated endophthalmitis.
  • Successful management of this complex case demonstrates the possibility of visual recovery and survival with aggressive multimodal therapy.