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Staphylococcus intermedius infections: case report and literature review

Nancy Wang1, Anne M Neilan2, Michael Klompas3

  • 1Department of Neurology, Brigham and Women's Hospital, Boston, MA ; Department of Neurology, Massachusetts General Hospital, MA.

Infectious Disease Reports
|January 29, 2014
PubMed

Insights

Staphylococcus intermedius, a bacteria common in dogs, can cause rare human infections, including prosthetic joint infections. Early diagnosis and tailored antibiotics are key for patient recovery.

Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Medical Microbiology

Background:

  • Staphylococcus intermedius is a common bacterium found in the skin and oral flora of dogs.
  • Human infections caused by S. intermedius are infrequently reported and often misidentified as Staphylococcus aureus.
  • Previous cases of human S. intermedius infections have been linked to close contact with dogs.

Observation:

  • A case of a 73-year-old female patient with a surgical wound infection caused by S. intermedius is presented.
  • The infection occurred one month after a total left elbow arthroplasty, marking the first reported instance of S. intermedius infecting a mechanical prosthesis in humans.
  • The patient's dog was presumed to be the source of the infection.

Findings:

  • The patient received antibiotic treatment, initially with vancomycin, followed by cefazolin and rifampin after antibiotic susceptibility results were available.
  • The patient showed a positive response to the tailored antibiotic regimen.
  • Case reports indicate that S. intermedius infections in humans generally respond well to appropriate antibiotic therapy, leading to significant recovery.

Implications:

  • This case highlights the potential for S. intermedius to cause invasive infections in humans, particularly prosthetic joint infections.
  • Clinicians should consider S. intermedius in the differential diagnosis of invasive infections in individuals with significant dog exposure.
  • Enhanced diagnostic awareness and prompt, targeted antimicrobial treatment are crucial for managing S. intermedius infections in human patients.
Keywords:
Staphylococcus intermediushumaninfectionpseudintermedius

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