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Related Concept Videos

Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

26
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...
26
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

906
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
906
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

24
Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
24
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

7.2K
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
7.2K
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

30
Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
30
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

46
The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
46

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Related Experiment Video

Updated: May 3, 2026

Transient Transduction of the Strobilated Forms of Echinococcus granulosus
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Transient Transduction of the Strobilated Forms of Echinococcus granulosus

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Primary pancreatic echinococcosis.

Padmaja Yarlagadda1, Bindu Madhav Yenigalla1, Uma Penmethsa1

  • 1Department of Microbiology, NRI Medical College & General Hospital, Chinakakani, Mangalagiri Mandal, Guntur, Andhra Pradesh, India.

Tropical Parasitology
|January 29, 2014
PubMed
Summary

Primary pancreatic hydatid cyst, a rare form of Echinococcus granulosus infection, was surgically removed in a 43-year-old Indian male. Diagnosis involved imaging and fluid analysis, confirming the zoonotic parasitic disease.

Keywords:
Hydatid cystinvaginated scolicespseudocyst

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Area of Science:

  • Medical Parasitology
  • Gastroenterology
  • Surgical Oncology

Background:

  • Hydatid disease is a common zoonosis in India, typically affecting the liver.
  • Extrahepatic manifestations, particularly primary pancreatic hydatid cysts, are exceptionally rare.
  • Pancreatic cysts can mimic other abdominal pathologies, complicating diagnosis.

Purpose of the Study:

  • To report a rare case of primary hydatid cyst in the pancreatic tail.
  • To highlight diagnostic challenges and successful surgical management of pancreatic echinococcosis.
  • To emphasize the importance of considering parasitic infections in pancreatic cystic lesions.

Main Methods:

  • Case presentation of a 43-year-old male with an abdominal mass.
  • Diagnostic workup included ultrasonography and computed tomography (CT) of the abdomen.
  • Surgical management involved splenectomy and distal pancreatectomy, followed by albendazole therapy.

Main Results:

  • Imaging revealed a large cystic lesion in the pancreatic tail, initially suspected as a pseudocyst.
  • Microbiological investigation of aspirated fluid confirmed Echinococcus granulosus by identifying free hooklets and invaginated scolices.
  • Histopathological findings correlated with the microbiological diagnosis of a hydatid cyst.

Conclusions:

  • Primary pancreatic hydatid cyst is a rare but important differential diagnosis for pancreatic cystic lesions.
  • Multimodality imaging and microbiological analysis are crucial for accurate diagnosis.
  • Surgical resection combined with antiparasitic therapy offers a successful treatment strategy for this rare condition.