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Bone Formation by Intramembranous Ossification

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Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...

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Updated: May 3, 2026

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

Tooth-derived bone graft material.

Young-Kyun Kim¹, Junho Lee², In-Woong Um²

¹Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.

Journal of the Korean Association of Oral and Maxillofacial Surgeons

|January 29, 2014

Summary

This summary is machine-generated.

Mammalian teeth can be processed into bone graft materials, offering potential for regenerative tissue engineering. Extracted teeth can be used to create scaffolds, bone grafts, and dental restorative materials.

Keywords:

Bone substitutes Demineralized dentin matrix Dentin Tissue engineering Tooth

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Last Updated: May 3, 2026

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Bone Conditioned Medium: Preparation and Bioassay

Bone Conditioned Medium: Preparation and Bioassay

Published on: July 8, 2015

Area of Science:

Biomaterials Science
Regenerative Medicine
Dental Research

Background:

Mammalian teeth contain growth factors and bone morphogenic proteins (BMPs).
Extracted teeth show potential for use in bone regeneration and as carriers for stem cells and growth factors.

Purpose of the Study:

To provide a broad overview of tooth-derived regenerative tissue engineering techniques.
To outline protocols and techniques for processing extracted teeth into bone graft materials.
To anticipate future developments in tooth-derived biomaterials.

Main Methods:

Comprehensive review of over 100 published papers on tooth-derived regenerative techniques.
Development of proprietary protocols and techniques for processing extracted teeth into bone graft material.

Main Results:

Successful extraction of growth factors and BMPs from mammalian teeth.
Established protocols for processing extracted teeth into bone graft materials.
Identified potential applications including scaffolds, homogenous/xenogenous bone grafts, and dental restorative materials.

Conclusions:

Extracted teeth are a viable source for regenerative tissue engineering materials.
Further research can lead to advanced scaffolds, bone grafts, and dental restorative applications.
Tooth-derived materials offer promising avenues for bone regeneration and dental restoration.